The BMPR1B Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to ALK6, BMPR1B, BR1b, and CDw293. This antibody recognizes Human antigen. The BMPR1B Antibody (Center) has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the bone morphogenetic
protein (BMP) receptor family of transmembrane serine/threonine
kinases. The ligands of this receptor are BMPs, which are members
of the TGF-beta superfamily. BMPs are involved in endochondral bone
formation and embryogenesis. These proteins transduce their signals
through the formation of heteromeric complexes of 2 different types
of serine (threonine) kinase receptors: type I receptors of about
50-55 kD and type II receptors of about 70-80 kD. Type II receptors
bind ligands in the absence of type I receptors, but they require
their respective type I receptors for signaling, whereas type I
receptors require their respective type II receptors for ligand
binding. Mutations in this gene have been associated with primary
pulmonary hypertension